T18: Predicting prostate volume, PSA, and PSA density


Objective:
Develop a model to predict three quantitative values from prostate MRI radiology reports:

  1. PSA level (ng/mL)
  2. Prostate volume (cm³)
  3. PSA density (ng/mL²)

Patient Population:
Radiology reports were collected from patients undergoing prostate MRI at:

  • Radboudumc
  • University Medical Center Groningen
  • Antoni van Leeuwenhoek Ziekenhuis

The dataset includes 1,616 cases.

Imaging Data:
Not applicable. The task is based solely on textual data — radiology reports written in Dutch.

Test Data:
Unlabeled radiology reports consistent in format with the training data. The model must output a List of three continuous (floating-point) values per report:

  • PSA level
  • Prostate volume
  • PSA density

Example: [68.0,9.7,0.14]

Reference Standard:
All labels were manually annotated by trained investigators. The reference values fall within the following ranges:

  • PSA level: 0 to 870 ng/mL (95% between 2–35 ng/mL)
  • Prostate volume: 4.0 to 470 cm³ (95% between 24–181 cm³)
  • PSA density: 0 to 171 ng/mL² (95% between 0.03–0.6 ng/mL²)

Evaluation Metrics:
Model performance is measured using Robust Symmetric Mean Absolute Percentage Error (RSMAPE) with the following epsilon thresholds:

  • PSA level: 0.04 ng/mL
  • Prostate volume: 4 cm³
  • PSA density: 0.04 ng/mL²

Relation to Existing Challenges:

  • Task 18 in the UNICORN challenge combines the following three tasks from the DRAGON challenge:

    • T19 (Prostate volume extraction)
    • T20 (Prostate specific antigen extraction)
    • T21 (Prostate specific antigen density extraction)
  • In UNICORN, these tasks are combined into a multi-label regression task, as opposed to single-label regression in the original DRAGON challenge.

Additional Resources: